Dates
Program Start Date:
Program End Date:
General information
Program Code:
21SCG-1D005
Budget:
55000000
AMD
The presented project aims to obtain new derivatives of azoles containing amino acid residues based on 1,2,4- and 1,2,3-triazoles which can be used in asymmetric synthesis as Brønsted bases and/or as ligands in catalytic reactions with transition series metals․ To study the catalytic activity of synthesized compounds in Michael addition, aldol and Darzen reactions, to evaluate their regio- and stereoselectivity depending on the structure of the reagent, substrate, and catalyst. If possible, study the catalytic activity of synthesized compounds with transition series metals: Pd, Cu, Ni, in catalyzed cross-coupling reactions, such as Tsuji-Trost, and evaluate their regio- and stereoselectivity.
